I went to my appointment with some trepidation yesterday. Although things have been going well with my treatment, everything I've been told so far is with regards to my Haemotological status and as good as it is to know that my blood counts are normal, it's always at the back of my mind that the old style drugs could achieve the same results. However with the new drugs, the disease should be affected at a molecular level.
Up until yesterday I didn't know how my cytogenetic response was? In short this is the molecular response i.e. is the Imatinib inhibiting the signal and stopping the mutation taking place.
Anyway the short answer is yes the new drug's working and in absolute spades. My BCR/ABL score has gone down from 107% to 8%. Don't ask me to explain what this means, because my consultant told me twice and I still haven't got a clue. However, she said that she would hope for a response like this after 6 months and actually it's occurred in 3. She has however warned that it may not shift at all in the next 3 months and may in fact bobble about a bit and this is just the way individual people respond to the drug.
Ultiimately they want to get me down to a tiny fraction of a percent at which point they can claim molecular remission, so I've got 15 months to wipe out this 8% and I'm going to try bloody hard at it.